quarta-feira, 10 de agosto de 2011

QUALITATIVE COMMENTS (3C-E; 3,5-DIMETHOXY-4-ETHOXYAMPHETAMINE)

(with 40 mg) It developed into a strange and indefinable something. It is unworldly. I am very much in control, but with an undertone of unreality that is a little reminiscent of high doses of LSD. If there were a great deal of sensory input, I might not see it. And if I were in complete sensory quiet I would miss it, too. But just where I am, I can see it. Eerie state of awareness. And by the 8th hour I am sober, with no residue except for some slight teeth clenching, and pretty much disbelieving the whole thing.

(with 60 mg) Visuals very strong, insistent. Body discomfort remained very heavy for first hour. Sense of implacable imposition of something toxic for a while. I felt at the mercy of uncomfortable physical effects faint or pre-nausea, heavy feeling of tremor (although tremor actually relatively light) and general disease, unease, nonease. Kept lying down so as to be as comfortable as possible. Fantasy began to be quite strong. At first, no eyes closed images, and certainly anti-erotic. 2nd hour on, bright colors, distinct shapes, jewel-like with eyes closed. Suddenly it became clearly not anti-erotic. That was the end of my bad place, and I shot immediately up to a +++. Complex fantasy which takes over hard to know what is real, what is fantasy. Continual erotic. Image of glass-walled apartment building in mid-desert. Exquisite sensitivity. Down by? midnight. Next morning, faint flickering lights on looking out windows.

This is an interesting closing of the circle. Although mescaline launched the entire show, the first half could be called the amphetamine period, with variations made on all aspects of the molecule except for that three-carbon chain. And it was found that the 4-substitution position was of paramount importance in both the potency and the quality of action of a compound. Then, looking at the long-ignored chain, lengthening it by the addition of a carbon atom eliminated all psychedelic effects and gave materials with reduced action. The action present was that of an antidepressant. But removing a carbon atom? This returned the search to the world of mescaline, but with the knowledge of the strong influence of the 4-position substituent. The two-carbon side-chain world was rediscovered, principally with 2C-B and 2C-D, and the 4-ethoxy-analogue of mescaline, E. This second half of the show could be called the phenethylamine period. And with compounds such as 3C-E which is, quite simply, Escaline (or E) reextended again to a 3-carbon chain amphetamine, there is a kind of satisfying closure. A fascinating compound, but for most subjects a little too heavy on the body.


n' PiHKAL: A Chemical Love Story, Dr. Alexander Shulgin & Ann Shulgin, 1991